51ΑΤΖζΘλΏΪ

Aaron Leconte – Chemistry

Professor Leconte and his research group published the article:

  • “Mutant polymerases capable of 2’ fluoro-modified nucleic acid synthesis and amplification with improved accuracy” inΒ Royal Society of Chemistry – Chemical Biology. Β This work was executed and co-authored in its entirety by four Keck Science Department undergraduates: Trevor Christensen (CMC ’22), Kristi Lee (SCR ’20), Simone Gottlieb (SCR ’21) and Mikayla Carrier (SCR ’21). Β In the work, they describe new methods for making the synthesis of unnatural forms of DNA more accurate. Β This work has implications for the use of unnatural DNA in medicine and disease diagnostics.

Link:

Full citation: T.A. Christensen, K.Y. Lee, S.Z.P. Gottlieb, M.B. Carrier, and A.M Leconte (2022). Mutant polymerases capable of 2’fluoro-modified nucleic acid synthesis and amplification with improved accuracy, RSC Chemical Biology, 3, 1044.

Tags